- Hyperthyroidism (an overactive thyroid gland)
- High blood pressure
- Cardiovascular strain or stress
Importantly, enlargement should be observed across several nails and over time before raising concern.
Disappearing Lunula:
In some cases, a lunula that seems to vanish entirely may point to deficiencies or fatigue, including:
- Chronic tiredness or lack of energy
- Iron deficiency
- Vitamin B12 deficiency
If the disappearance occurs on just one nail, it’s usually not meaningful. But if it happens across both hands, especially with other symptoms like pale skin or weakness, a medical check may be worthwhile.
Color Shifts:
The color of the lunula can also provide subtle hints. While natural lighting and temperature changes can alter its look, persistent discoloration deserves attention:
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